CURRICULUM VITAE

     Name:  COSSON Jacky, Jean-Claude, Robert

Birth date and place:  16 November 1944 in Issoudun - 36100 – FRANCE

Citizenship: French

Employment: Research Director at the CNRS (equivalent to full professor) 1969-2011

Transient position: Professor at University of French Polynesia (one year-2009)

Present days: Half-time Professor at University of South Bohemia, Czech Republic since 2011.

E-mail address = [email protected] 

WEB sites = http://www.obs-vlfr.fr and http://www.frov.jcu.cz/en/vurh-frov-ju/vurh-ju-ve-vodnanech                                                                                               

University degrees: Masters in Biochemistry and Biophysics (1964-68), DEA (first thesis) in Biophysics (1969) - Faculty of Sciences of PARIS-ORSAY (France).

PhD: State Thesis defended in 1977 = mitochondrial ATPase in yeast mutants. Molecular Genetic Centre- CNRS - Gif sur Yvette - (France- 1971-1977).

Ability to direct PhD: associated with State Thesis

Dhc: Doctor Honoris causa at University of South Bohemia, Czech Republic (2009).

Postdoctoral stays: 1^st- Labelling by photoaffinity of ATP binding site in mitochondrial ATPase - Pr Guillory lab- University of Hawaii- USA- 1977                       

2^nd- Genes sequencing of the mitochondrial ATPase subunits - Pr Tzagoloff’s lab - Columbia University. New York, USA- 1978.

Recent research topics:  

- Cell fate during early differenciation in sea urchin embryos

- Molecular biology of histone genes expression during this period

- Caracterisation of chemotaxis of eggs towards spermatozoa

- Structure and function of flagellar axoneme and associated para-axonemal organelles in marine protists and in Trypanosomes.

- Structure and function of nanofilaments of 2-4 nm in the cytoskeleton.

- Function of axonemes in bronchial human cilia and in cilia of sea urchin embryos

- Initiation and regulation of motility of flagella in various species (sea urchins, fish, human, shellfish, arenicola, chlamydomonas, etc)

- Aquaculture of different organisms (dinoflagellate, trout, carp, tench, silurid, sturgeon, salmon, turbot, cod, halibut, shell-fishes, etc)

- Elaboration and caracterisation of anti-flagellar movement antibodies.

- Elaboration of technologies for high-speed video recording of moving flagella in various species.

- Physiology of spermatozoa in various species: fish, mollusks, sea urchins etc.
- Sperm guidance at sperm/egg meeting in fish species.
- simulation and modelisation of fish sperm swimming.

International collaborative Programs & Research Grants

- with Univ. of Hawaii & with Univ. of Columbia, New York, during post-doc stays (1977-78).

- EMBO short-term fellowship: laboratory of Dr M. Busslinger Lab. of Molecular Biology- University of Zurich (1987) = regulatory sequences of DNA upstream of histones genes.

- Exchange program MRC-CNRS of the Ministry of Foreign Affairs (France-Québec) = in 1987-88: role of proteases in the axonemal machinery and in 1989-93 and 93-99 = elaboration of monoclonal anti-bodies against axonemal proteins and stays in the lab of Dr C. Gagnon, University of Mc Gill, Montréal.

- Research grant (URM - 1994-99) on the motility of marine fish spermatozoa: collaboration with the laboratory of Ichthyology (Pr R. Billard) Museum of Natural History, Paris and Direction of Living Resources, IFREMER, Brest.

- Exchange program CNRS-NSF (USA) and NATO support in 1995-96 to J. Cosson & R. Miller (Temple Univ. USA) for studies on Salps (jelly-fish) spermatozoa.

- Research grants with IFREMER (1994-99) to J. Cosson for studies on the triggering of motility in oyster and scallop spermatozoa.

- Participation to research grant of the EEC in 1994-97 = Collaboration with the “Danube Delta Inst.” Romania, with the Inst. of Fish Culture- Czech Republic, with the “Aristotle Univ.”- Greece, with the Museum of Natural History MNHN- Paris, with the INRA- Jouy en Josas, & with the CYSAAF- Rennes) on the topic of “Genetic and reproduction of European Silurid fishes”.

- Research grants with “PROTAGORAS” to J. Cosson on the triggering of motility of the Silurids (catfish) spermatozoa (collaboration with INRA/France in Rennes and the CEMAGREF in Montpellier, 1995-96).

- Research grants in 1989-91 with the INRA (GCS/BBA, Activation of carp spermatozoa and with Ministry of Research & Technology (ITAVI, Artificial reproduction of catfish Silurus glanis)

- Exchange programs with Japan (supported by the JSPS): studies of marine dinoflagellates: stay of 3 months in 1991 at the Marine Station in Sugashima, Univ. of Nagoya, Japan and one month stay in Misaki Marine Station (Univ. Tokyo) in 1999.

- Grant and collaboration with Dr Koichi Kato, Univ. Nagoya, Japan, visitor in France for 6 months in 1989, for studies on marine dinoflagellates.

- Grant & collaboration with Dr Allan Pacey from Gatti Marine Lab. in St Andrew (Scotland), one-year post-doc (1991-92) on the maturation and triggering of motility in spermatozoa of Arenicola (marine worms).

- Grant of the Ministry of Foreign Office “Alliance Project” with U.K., M. Holwill, King’s College- London and H. Delacroix CNRS Gif-France, obtained in 1996-97.

- Grant of US Ministry of Agriculture with Dr S. Mims, Aquaculture Center, Kentuky Univ. & Eastern European countries, to study the biology of spermatozoa of sturgeon & paddle-fish (1996-99 and 2002-05).

- Participation to research grant of the "Reprodot ", EEC program on Tuna fish reproduction in 2005 = studies on tuna sperm motility in Spain. 

- Collaboration with Laboratory of Yang-Tsé River Fisheries Institute, JingZhou, China, on sturgeon and paddlefish gametes and reproduction. 2006.
- Invited professor for one year in Tahiti (University of French Polynesia).

- Recipient of a grant from the Grant Agency Czech Republic 502/12/1973. Characterization of swimming fish sperm flagella: biophysical quantification (2012-2015, leader Jacky Cosson)

- Participant to a grant from the Grant Agency Czech Republic P502/11/0090. Maturation and ageing of fish spermatozoa: a comparative study between teleostean and chondrostean fish species as taxonomically distant models(2011 - 2015, leader Marek Rodina).

- Recipient of two grants of three-years duration from the Grant Agency Czech Republic (CSF No. P502/15-12034S). 1- Ancient mechanism of sturgeon sperm for acquisition of ability to fertilize (leader J. Cosson) and 2- Identification of cellular events resulting from maturation process: identification of maturation factor on sperm surface, changes in flagellum behavior and acrosome during maturation process (leader J. Cosson).

- CENAQUA CZ.1.05/2.1.00/01.0024. South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses (2010 - 2013, responsible Prof. Otomar Linhart)

- Recipient of a grant from COST-Aquagamete European Project to organize an International Workshop on "Microscopy and Image Analysis", Vodnany, Czech Rep. (March 2015).

- Recipient of a 3 months position of Investigator for studies on reproduction of local fish species (Fondecyt MEC 80140066 and 1151315) in Oct. to Dec. 2015, in the Univ. Catholica of Temuco, Chile.  

Collaborations with foreign laboratories:

- Dr Koitchi Kato, Nagoya Univ. Japon : mitosis in dinoflagellates.

- Dr B.J. Anderton, Queen Mary College, London, GB: monoclonal antibodies anti-intermediate filaments

- Dr J.L. Salisbury, Center for Neuroscience, Cleveland, USA: centrin of  basal bodies.

- Prof. Claude Gagnon, Mac Gill Univ., Montréal, Canada :  proteases et antibodies "anti-movement" in axonemes of flagella.

- Dr David Brown, Univ Ottawa, Canada: microtubules labelling in cells.

- Prof. Michel Wright, Centre de Toxicologie Moléculaire, CNRS Toulouse :  centrosomes.

- Prof. Joseph Shrevel et Jean-Louis Justine, Muséum Hist. Nat. Paris: ParaFlagellar Roots in trypanosomes & microtubules.

- Profs. H. Sato & H. Hayachi , Sugashima Marine Station, Univ. Nagoya, Japon : Polarisation microscopy and nanofilaments.

- Prof. M. Bentley, Gatti Marine Station, St Andrew, Scotland: Spermatozoa activation in arenicoles.

- Prof. Roland Billard, Museum of National History, Paris: initiation of swimming in fish spermatozoa.

- Prof. Otomar Linhart, Inst. Pisciculture, Vodnany, Tzech Rep.: initiation & conservation of spermatozoa in Silurids, sturgeons, paddle fish, tench, carp.

- Dr M. Busslinger, Institüt für Molekular Pathologie, Univ. of Vienna, Austria: histones genes.

- Dr T. Maruyama, Marine Biotech. Inst., Manazuru, Japan: confocal microscopy of chromosomes in Dinoflagellates.

- Dr Didier Job, INSERM, Grenoble, France: microtubules & flagellar movement.

- Dr Marc Suquet, IFREMER Brest: initiation & cryoconservation of turbot, cod and oyster spermatozoa.

- Dr Maurice Loir, INRA Rennes, France:  initiation & conservation of spermatozoa in Trout.

- Pr Damien Schoëvaërt, Hopital St Louis Paris:  modelisation of axonemal movement. 

- Pr Leslie Crim, Univ. of St John Newfoundland, Canada:  initiation & conservation of spermatozoa in Halibut.

- Dr Nicole Devauchelle, IFREMER Brest, France: initiation & conservation of spermatozoa in Scallops.

- Pr Steve Mims, Kentuky Aquaculture Center - USA: movements of spermatozoa in Paddle-Fish

- Pr André Adoutte, University of Orsay, France: polyglycylation of tubulins & movement of sperm flagella

- Dr Hervé Delacroix, CNRS, Gif sur Yvette, France: modelisation of flagellar & ciliary movement 

- Pr Richard Miller, Temple Univ. USA:  chimiotactisme of spermatozoa in Salps (marine planktonic animals)

- Dr Bernard Eddé, Collège de France, Paris - France: polyglutamylation of tubulins and movement of spermatozoa.

- Dr Marc Legendre, IRD, Jakarta, Indonesia and Montpellier, France: Fish sperm movement in various species.

- Dr M. Okuno, University of Tokyo - Japan: movement of spermatozoa in trout.

- Pr Michael Holwill, King’s College – London, UK: modelisation of the axonemal movement.

- Dr M. Gualtieri CNR Italy, Pisa, Istituto di Biofisica, Studies on unicells movement.

- Pr Masaaki Morisawa, Misaki Marine Station (Univ of Tokyo): sperm/egg chemotaxis in tunicates.

- Pr David Kime, Univ of Sheffield (UK):  techniques of computer assisted evaluation of fish sperm movement quality 

- Dr Andrzej Cieresko, Polish Academy of Sciences, Poland. Fish sperm movement.

- Dr A. Pourkazemi, Sturgeon Center, Racht, Iran, Sturgeon gametes and reproduction.

- Dr Christian Fauvel, IFREMER, Palavas, France:  movement of tuna and sea bass spermatozoa.

- Zhang Xianliang, Laboratory of Yang-Tsé River Fisheries Inst., Jing Zhou, China, on chinese sturgeon reproduction and movement of their spermatozoa.

- Dr Belinda Hui, IFREMER (French Polynesia) Tahiti, reproduction and cryo-conservation of black pearl oysters.

- Prof. Marina Schneider, University of French Polynesia (Tahiti) on sperm motility in black pearl oysters.

- Dr Igor Babiak, Bodo University, Norway, on salmon, cod and halibut sperm movement.

- Dr K. Inaba, Shimoda Marine Research Center, University of Tsukuba, Shizuoka, (Japan) on Fish sperm motility activation.

- Dr M. Yoshida, Misaki Marine Biological Station, University of Tokyo, Miura, Kanagawa (Japan) on egg/sperm chemotaxis in various species.

- Dr A. Pacey & E. Gillies, Univ. Sheffield (UK) modelisation of sperm flagella movement.

- Prof. E. Gaffney, Dept Biol. Mathematics, Univ. Oxford (UK) Fish sperm flagella movement modeling.

- Kenta Ishimoto, Dept of Mathematics, Univ. Kyoto (Japan) Flagella of fish spermatozoa: modelisation.

- Prof. Juan Asturiano, Univ. of Technology, Valencia (Spain) Study of eel sperm flagella.

- Prof. Carles Soler Vasquez, Univ. of Technology and Proiser company, Valencia (Spain) Studies on mammalian sperm flagella.

- Prof. Ivan Valdebenito, Catholic Univ. of Temuco (Chile). Studies on salmonid and local fish species spermatozoa.

- Prof. Jorge Farias, Univ. de La Frontera, Temuco (Chile). Studies on salmonid spermatozoa.

Teaching & participation to research training:

-Hélène Godart : PhD thesis (1991-92) University of Nice – France = Purification of nanofilaments (para-axonemal rod in planktonic dinoflagellates)

-Dr Christian Redondo Spain: PhD, Veterinarian Doctor (1990) = Activation of carp spermatozoa.

-Dr Claude Clary-Meinez: Supervisor of PhD thesis, University of Nice – France = Regulation of bronchial cilia

-Dr Allan Pacey, Gatti Marine Station, St Andrew, Scotland = Post-Doc (one year stay & fellowship of Royal Society, London) on activation of Arenicola spermatozoa.

- Françoise André, laboratory of Ichthyology, Museum of Natural History, Paris, France, supervisor of D.E.S. (Master degree) on maturation of carp spermatozoa and role of seminal fluid (1989-91), 

- Dr Ghislaine Perchec, laboratory of Ichtyologie, Museum of Natural History, Paris, France; supervisor of PhD on Energetic (ATP) & activation of carp spermatozoa (1992-96)

- Prof. Laurent Chauvaud, Lab. IFREMER Brest, supervisor of D.E.A. (pre-doctorant) on activation of turbot spermatozoa (1992-93).

- Dr Catherine Dreanno, Laboratory of IFREMER Brest & laboratory of Ichthyology, Museum of Natural History, Paris, France; supervisor of PhD (french Doctorat) on activation & energetic of turbot spermatozoa (1995-98).

- Supervisor of stays of students from Institut Universitaire of Technology of Clermont-Ferrand, France, every year from 1989 to 2005 (stays of 3 months per year).

- Participation to teaching in Biochemistry Departementt (University of Nice- France) on Cytoskeleton, Cell Biology and in Developmental Biology (University P. M. Curie, Paris 6, France). 

- Participation to the European ERASMUS program, supervisor of student stays of 3 months every year (1991-2003)

- Participation to practical stays of Master students from University P. M. Curie, supervisor of student stays of 1 or 2 weeks every year (1991-2003) on Developmental Biology.

- Participation to teaching in the Biology Program of University of South Bohemia, Czech Republic (1999 – 2009).

- Participation to teaching in the Marine Biology Summer-school in Misaki Marine Station, Univ. Tokyo. (Spring 2007 and 2013) 

- Workshop on Sturgeon Sperm Cryoconservation, Racht, Iran (May 2002)

- Workshop on Fish Sperm Movement, Vodnany, Czech Republic (March 2007)

- Teaching as invited professor during 13 months at the University of French Polynesia (2009-10).

- Participation to teaching in the Summer School Program of the Faculty of Fisheries, Univ. of South Bohemia, Czech Republic (2012 to 2015).

- Participation to teaching and workshop programs at Catholic University of Temuco, Chile in 2011, 2012 & 2015.

- Professor & Research Investigator since 2010 at Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Vodnany, Czech Republic.

- Supervisor of four PhD students of the above Faculty: Volodymyr Bondarenko, Viktoria Dzyuba, Galina Prokopchuk and Ievgeniia Gazo (PhD topics dealing with fish sperm motility).

- Consultant of several PhDs in the same faculty.

- Collaboration to supervise several PhD students of the Univ. De La Frontera (Temuco, Chile).

Other functions or activities: 

- Former member of the editorial board of the journal "Cell Biology International" from 1991 to 2012.

- Co-organiser of the "International Symposium of Cell Motility" in 1985 et 1992 à Nice Sophia-Antipolis, and of the international meeting on the "Conservation of animal gametes for aquaculture purposes" in Paris (1992), and an EMBO summer school en 1989.

- Co-organiser of the “8th Int. Symposium of Spermatology” Montreal 1998.

- Co-organiser of several workshops: in Villefranche sur mer (France) in 2003 to 2006 on microtubules; in Czech Rep. in 2006 and 2007, on sperm motility evaluation.

- Organiser of two workshops (5 days) on "Optical Microscopy and Image Analysis" in Vodnany (Czech Rep.) in 2014 & 2015 (the later supported by the "COST" of E.U.).

- Stays in foreign countries for research purposes: 1- one year post-doc (1977) in Pr Guillory's lab, Univ. Hawaii USA -2- one year post-doc (1978) in Pr Tzagoloff's lab, Columbia Univ., New York USA -3- Yearly stays of 2 to 4 weeks in Pr Gagnon's lab, Mac Gill Univ., Montréal Canada, from 1985 to 2005 -4- one month stay (EMBO fellowship in 1987), in Dr Busslinger's lab, Univ. Zurich Switzerland -5- stay of 2 weeks in Taïwan in1991, -6- stay of 3 months (1991) in the Marine Station of Sugashima, Nagoya Univ. Japan. -7- Yearly 2 weeks stays in Czech Republic from 1994 to 2010, in USA from 1995 to 2003 and in 2012, in Indonesia (1999 & 2000) and in Romania in 95 -8- stay of 2 weeks in Iran in 2002 -9- 4 stays of 1 month (1998, 1999, 2002 & 2003) and 1 week in 2012 in Misaki Marine Station, Univ. Tokyo, Japan -10- stay of 2 weeks in Mexico (2003) -11- stay of 3 weeks in Yang Tse River Research Institute in China (2006) -12- Three weeks stay in Bodo University, Norway -13- One months stays in Temuco University Chile in 2011, 2012 and 3 months in 2015.

- Participation to 36 International Meetings, among which, 25 as invited speaker and/or chairman.

- Conferences and lectures in: Japan, USA, Canada, Switzerland, Germany, Rep. of Taïwan, Czech Republic, Romania, Australia, Indonesia, Rep. of Iran, Mexico, China, Polynesia, Chile, Poland, Italy, United Kingdom, Norway, Hungary, Spain.

- Co-editor of a scientific book: “Fish Spermatology” S.M.H.Alavi, R. Rafiee, K. Koward  and J. Cosson Eds, Alpha Sience, 2007.

- Editor of an e-book: "Flagellar Mechanics and Sperm Guidance " Ed. Jacky J. Cosson; 426 pages; 12 chapters; 26 contributing authors; Publisher: Bentham Science Publishers Ltd., United Arab Emirates; Electronic version eISBN: 978-1-68108-128-1,2015 Printed version: ISBN: 978-1-68108-129-8.

- Co-editor of a special issue of "Theriogenology" in 2019.

- Painter, photographer and videographer. Optical microscopy conceiver.